BioPerine®

Product Description

BioPerine® is a standardized extract obtained from the black pepper fruits (Piper nigrum) and standardized for a minimum of 95% Piperine. It is co-administered with various nutrients to enhance their bioavailability in both humans and animals.

Black pepper is considered the “King of Spices” throughout the world due to its pungent principle piperine, which is used as a potent bioavailability enhancer.

Benefits

Piperine from BioPerine® is used as a bioavailability enhancer

Piperine from BioPerine® is used as a bioavailability enhancer

Piperine from BioPerine® is co-administered with various nutrients to enhance their bioavailability in both humans and animals

Piperine from BioPerine® is co-administered with various nutrients to enhance their bioavailability in both humans and animals

Piperine helps to enhance the absorption of nutrients

Piperine helps to enhance the absorption of nutrients

Product Benefits

Plant-based

Plant-based

Self-affirmed GRAS

Self-affirmed GRAS

98 Publications with 72+ Clinical studies

98 Publications with 72+ Clinical studies

Safety and efficacy are well supported by scientific evidence

Safety and efficacy are well supported by scientific evidence

The only black pepper product with original patented status as a bioavailability enhancer

The only black pepper product with original patented status as a bioavailability enhancer

Has a long history of usage as a bioavailability enhancer

Has a long history of usage as a bioavailability enhancer

Traditional Uses

Black pepper has been used traditionally in the human diet since ancient times. It is one of the most widely used spices in the world. It is widely used in various traditional medicines, preservatives, and health supplements.

Out of 370 compound formulations listed in the Handbook of Domestic Medicines and Common Ayurvedic Remedies, 210 contain either Trikatu (meaning three acrids) or its individual ingredients (i.e. black pepper, long pepper, and ginger). In Ayurveda, Trikatu has been described as a major decoction useful in restoring the imbalance of Kapha, Vata and Pitta.

Usage & Support

Shelf life

5 Years It should be stored in closed containers at room temperature

Suggested Use

5 mg per serving

Ingredient Code

0215

Resources

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FAQs

  • A natural ingredient that significantly improves the bioavailability of nutritive compounds
  • A standardized extract from the fruits of Piper nigrum (black pepper) with self-affirmed GRAS status.

BioPerine® contains 95 to 99% pure piperine.

  • Piperine content in BioPerine® is much higher (95-­99% pure piperine) than it is in black pepper (piperine is only 3-­9% in all parts of black pepper)
  • A standardized extract allows a wide range of applications other than the traditional use of black pepper

Piperine enhances the bioavailability of nutritive substances through the following mechanisms:

  • Modulation of P-glycoprotein-mediated Nutrient efflux
  • Modulation of Metabolic Enzymes involved in Biotransformation of Nutrients
  • Enhanced Intestinal Absorption
  • Thermogenesis

BioPerine® has been shown to enhance the bioavailability of the following groups of nutrients in humans and animals:

  • Herbal extracts (Curcumin C3 Complex®, Sabroxy®, Curcousin®, Cirpusins®, and Panax ginseng)
  • Water soluble vitamins
  • Antioxidants (Beta­‐carotene, Selenium, Coenzyme Q10, Epigallocatechin-3-Gallate, Resveratrol)
  • Minerals (Iron and Selenium)

The bioavailability of Curcumin C3 Complex®, Coenzyme Q10, Beta carotene, L-(+)-Selenomethionine, Se-Methyl-L-Selenocysteine, Vitamin B6, Resveratrol and BioIron™ (Organic Elemental Iron) was evaluated in humans with the administration of BioPerine®.

Yes, piperine is extracted from sustainably grown Piper nigrum.

Yes, BioPerine® is NON-GMO Project Verified.

Yes, BioPerine® is Allergen free, Kosher and Halal certified.

  • Yes, BioPerine® is an Old Dietary Ingredient.
  • BioPerine® can therefore be formulated in dietary supplements immediately without the need of pre‐market NDI notification.

The suggested dose is 5 mg per serving.

  • Sabinsa manufactures BioPerine® in cGMP manufacturing facilities
  • They are FDA‐inspected and passed

  • Yes, BioPerine® is a globally trademarked ingredient
  • Please see www.bioperine.com

Certifications

Non-GMO Project Verified

Non-GMO Project Verified

Kosher and Halal certified

Kosher and Halal certified

Self-affirmed GRAS

Self-affirmed GRAS

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